Review of Molecular Interactions, States of Matter, Kinetics & Thermodynamics

These lectures are intended to review the important concepts that were introduced last semester and at the start of this semester and lay groundwork for the rest of this semester. We will refer to both the text you purchased "Pharmaceutical Dosage Forms and Drug Delivery Systems", 7th Edition, by Ansel, Popovich and Allen and to the reference text "Physical Pharmacy 4th Ed" by Alfred Martin throughout the course.
 

Lets all become involved in answering the following questions

- What is the difference between ionic, covalent and metallic bonds?
- What are the characteristics that differentiate the states of matter?
- What does the Clausius-Claperon equation apply to?
- What is the difference between coal, diamond and graphite?
- F=C-P+2 describes what ?
- What does this equation describe E=Q-W
- What is an adiabatic process?
- Define Enthalpy and contrast it with Entropy. How are they related to free energy?
- What does Lord Kelvin and the third law of thermodynamics have in common?
- What is the difference between rate and rate constant?
- What is a fluid?
- What is a solution?
- What are the factors that affect dissolution?
- What is the difference between rate and extent of dissolution?
- What is meant by order of a reaction?
- What is the relationship between energy of activation and rate of reaction?

Topics and pages from "Ansel" you should have already covered

Topic
 Page Numbers
Melting Point Depression 98
Solubility and Distribution Phenomena
Phase Rule		 101 & 104
99
Stability, Kinetics, and Shelf Life 115 & 118
Dissociation Constants 112
Colligative Properties of Drugs 453
Milliequivalents 453
Osmolality and Tonicity 453
pH and solubility, and Buffers 102, 104, 112, & 548
 


When was the last time you did a problem that involved one of these concepts.  How does Thermodynamics help us understand these concepts??